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Because these medications work in part by slowing how quickly food leaves the stomach, the most frequent GLP-1 side effects are gastrointestinal symptoms, such as: Nausea Vomiting Diarrhea Constipation Upset stomach or heartburn These symptoms are usually most pronounced during the first few weeks of treatment or after a dose increase

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So if you already have heart failure, using Humira may worsen it

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