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One phase 2 trial looking at whether GLP-1s could reduce the use of opioids in people with opioid use disorder has started recruiting participants

(2024) real-world study, adverse events were reported more often with oral semaglutide (16.7%) than with injectable semaglutide (4.9%), and discontinuation due to side effects was also more common in the oral group

Neeland also mentioned that there is an oral semaglutide option that is not currently experiencing shortages and is indicated for diabetes management

Clinical Insight: The balance between reduced (GSH) and oxidized (GSSG) forms shows your body's oxidative stress level