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In adults with type 2 diabetes mellitus and established/high risk of ASCVD, treatment regimen should include agents that reduce cardiorenal risk, such as an SGLT2 inhibitor or a GLP-1 receptor agonist

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These details matter most for researchers running extended protocols or working with precise dose requirements

For example, some patients with Medicare discovered their expensive GLP-1 therapy (for CV risk reduction) was denied without explanations, leading to legal and public policy debate ( [21] ) ( [65] )