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Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss
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Starting Dose: New patients typically begin with 0.25 mg once weekly for 4 weeks
Additional considerations include structural gynecological pathology such as endometrial polyps, uterine fibroids, adenomyosis, or cervical lesions, which are common in reproductive-age women and may be incidentally discovered during evaluation
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