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Individuals taking metformin alongside Mounjaro face increased risk of B12 deficiency, as metformin is known to impair B12 absorption, and may require more frequent monitoring

Metformin should be preferred to glitazones due to the adverse effects on bone and fluid retention of the latter

Thus, an understanding of the various disorders and substances that can contribute to oral and perioral pigmentation is essential for the appropriate evaluation, diagnosis, and management of the patient

[14] [15] It is important to note that these two precursors have different regulatory statuses in the UK

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Retatrutide remains in clinical development and is not approved for general prescribing or self-administration in the UK