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Phase 2 results at 48 weeks (Jastreboff et al., NEJM 2023): Phase 3 TRIUMPH-4 at 68 weeks (Lilly Press Release, Dec 2025): The 12 mg dose produced 28.7% body weight loss, an average of 71.2 lbs from a 248.5 lb baseline

Per the Egrifta prescribing information, a missed dose is skipped and dosing resumes on the next scheduled day without doubling up

2003 Feb;24(2):307-11

"Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues." Trends in Molecular Medicine

Grant 315247/2020-7), Fundao de Amparo Pesquisa do Estado de Minas Gerais (FAPEMIG

Sample sizes per experimental group were chosen based on previously reported similar studies [4, 5]