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[28] Clinical significance [edit] In addition to their roles in cancer development and chemotherapeutic drug resistance, GSTs are implicated in a variety of diseases by virtue of their involvement with GSH

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While generally well-tolerated, these medications may have side effects like gastrointestinal disturbances (nausea, vomiting, diarrhea) that often subside over time

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J Cell Biol 220(9):e202105043 Gao M, Monian P, Quadri N, Ramasamy R, Jiang X (2015) Glutaminolysis and transferrin regulate ferroptosis