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At this stage, I often see: Typical cumulative loss by 3 months: 1225+ pounds 512% of starting body weight This is where tirzepatide often clearly outperforms older medications
Survodutide (Boehringer Ingelheim, Phase 3 SYNCHRONIZE) and mazdutide (Innovent, approved in China, filed ex-China) both sit in the ~14-18% placebo-adjusted range at their highest-dose arms - comfortably above semaglutide, comfortably below the triples
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