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Prescriptions of these drugs increased by 400% from 2021 to 2023 in the United States alone 1

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Long-acting agents (e.g., dulaglutide, semaglutide, and liraglutide) provide better control of fasting glucose and HbA1c levels

Its safety profile is generally favorable, but several specific considerations deserve clinician attention particularly around copper biology, zinc balance, and the small number of patient populations where caution or contraindication applies

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