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Muscle tissue burns roughly three times more calories at rest than fat tissue, meaning that preserving muscle during weight loss helps maintain metabolic rate and reduces the likelihood of weight regain

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Due to the long duration of diabetes, T2D patients have higher risks of macrovascular and microvascular damage, as well as other severe complications, such as diabetic nephropathy, diabetic cardiomyopathy, non-alcoholic fatty liver disease (NAFLD), diabetic retinopathy, cognitive impairment, that cause mortality (Gregg et al., 2014)

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This effect reduces appetite and supports weight loss, making them increasingly popular beyond diabetes treatment

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