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Zhang W, Yang S, He H, Liu C, Chen W, Tang X

10.1111/1440-1681.12659 9 ChanY

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Seccombe, D

found that cardiac microvascular endothelial cells isolated from T2DM mice exhibited increased expression of pro-ferroptotic genes (Tfrc, Acsl4, Ptgs2), decreased expression of anti-ferroptotic genes (Gpx4, Slc7a11), and elevated lipid peroxidation (MDA, 4-HNE), indicating that hyperglycemia also induces ferroptosis in endothelial cells [97]

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