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Sin embargo, dependiendo de la composicin de la microbiota intestinal, el riesgo de tener un evento adverso cardiovascular puede ser menor en individuos con TMAO circulante bajo versus alto, incluso aunque las concentraciones de colina y/o betana en la sangre estn elevadas (115)

In addition to lowering the levels of blood glucose, as shown in Figure 1 , GLP-1RAs have also been shown to have a positive effect on multiple human tissues

The Biochemical journal

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For example, in a separate pooled analysis of 4 major clinical trials reporting cardiovascular events in patients with T2D and CKD, Kelly et al