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Conclusion GLP-1based therapies are reshaping how clinicians approach cardiometabolic risk
Some plans cover semaglutide (Wegovy) or tirzepatide (Zepbound) with copays of $25-$300/month, but many plans dont cover weight loss medications or require extensive prior authorization
CagriSema 2.4 mg / 2.4 mg demonstrated 22.7% mean weight reduction in adults with overweight or obesity in REDEFINE 1, published in NEJM
many subjects with type 2 diabetes saw improvements in their blood sugar regulation, too
Candidates for Semaglutide have a BMI over 30, or over 27 with at least one related condition such as high blood pressure, high cholesterol or diabetes (Type 2)
Medication interactions and pancreatitis screening should inform baseline evaluation
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