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This is primarily due to its superior efficacy in achieving significant weight loss outcomes
Notably, higher levels of infiltration of fat into muscles are associated with decreased muscle strength and deficits in function
Furthermore, another study highlighted GLP-1 RAs direct impact on the brain, especially the hypothalamus 40
There's randomized controlled trials
As ghrelin induces hunger, inhibition of the ghrelin receptor represents an attractive therapeutic target in obesity
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