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The study found no impact on folate levels, but reported a 5% reduction in serum B12 levels when women went from 0 to 30 g of alcohol a day

This chart may be useful as an overview: What Are The Symptoms of Vitamin B12 Deficiency

(What the Evidence Shows) Short answer: not on their own

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Metabolic B12 deficiency is prevalent, impacting 10%-40% of the population

The process typically takes 30 to 60 minutes, during which you relax in a comfortable chair while the solution is administered