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Regular check-ups and dosage adjustments help ensure long-term effectiveness while minimizing side effects

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While long-term glycemic control unequivocally reduces the risk of developing and progressing diabetic retinopathy (as demonstrated in the DCCT and UKPDS trials), rapid reduction in blood glucose levels can paradoxically cause temporary worsening of existing retinopathya phenomenon termed "early worsening" or "acute progression

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doi: 10.1155/2013/956792 221 PolonikovA

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