This study explored whether GLP-1RA use in T2DM was associated with a reduction in CRC risk
In clinical trials of GLP-1 receptor agonists, treatment discontinuation has varied between studies and between individual drugs [7,8,9,10,11,12,13]
The most common side effects of GLP-1 analogues are nausea and vomiting, which have been attributed to delayed gastric emptying [14,15,16]
What Are GLP-1 Weight-Loss Drugs and How Do They Work
For instance, a study in 72 obese subjects demonstrated that 20 weeks on semaglutide 2.4mg/weekly caused a 35% decrease in caloric consumption during a free, unrestricted test meal when compared to placebo [13]
A: *The CV risk score was derived as the predicted values from a Cox proportional hazard regression of time to first MACE, where all significant baseline predictors, except randomized treatment, were included as explanatory variables