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Clinically, GLP-1RAs like semaglutide induce sweet hyposensitivity and reduce preference for hyperpalatable foods, an effect mediated by changes in endogenous GLP-1 secretion and synaptic plasticity in reward circuits (166)

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To mitigate side effects, healthcare providers recommend starting with a lower dose and gradually increasing it over time

Mazdutides GLORY-1 trial publication in the New England Journal of Medicine marked the first time a clinical study of an innovative metabolic therapy developed in China appeared in this prestigious journal

The last thing any scientist needs is uncertainty about their foundational materials