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Vitamin B12 deficiency in over 16s: diagnosis and management (NG239) Recommendations

The evidence supporting it comes mostly from clinical observation and patient-reported experiences, which provide useful context but are not the same as controlled trial data

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Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria

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