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Phase 2 weight loss (48 weeks): 8.7% at 2 mg maintenance 4 mg Weeks 58 First dose where therapeutic effects become clinically meaningful
Gastaldelli A, Cusi K, Fernndez Land L, Bray R, Brouwers B, Rodrguez
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A parallel line of work by Chang and colleagues (J Appl Physiol, 2011) examined cultured rat Achilles tendon fibroblasts and reported increased outgrowth, survival and migration alongside elevated phosphorylation of focal adhesion kinase (FAK) and paxillin, the adaptor pair coupling integrin engagement to cytoskeletal reorganisation
Nutrition Bulletin, 33 (1), 15-25
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