ALA may be helpful for: People with diabetic neuropathy: ALA has the strongest clinical evidence for reducing nerve pain and improving quality of life in this group.1 Those with type 2 diabetes or metabolic syndrome: Modest improvements in insulin sensitivity and blood sugar markers have been observed in some studies.24 People with high oxidative stress: Research shows that ALA can help lower oxidative stress markers like CRP in individuals with chronic inflammation or metabolic risk factors.27 Those with nerve-related conditions or mitochondrial dysfunction: Early research suggests ALA may help support nerve health in contexts like multiple sclerosis.3 However, ALA may not be appropriate if: Youre generally healthy and eat a balanced diet Your body naturally produces some ALA, and small amounts are found in foods like spinach, broccoli, red meat, and organ meats.41 In healthy individuals, taking an ALA supplement may offer little to no added benefit

This type of fiber will stimulate the growth of healthy bacteria
10.1097/MCC.0b013e32834e7c3a 27 HrelecM.KlicekR.BrcicL.BrcicI.CvjetkoI.SeiwerthS.et al (2009)
Collagen supplementation: Oral collagen peptides (10-15g daily) provide specific amino acids (glycine, proline, hydroxyproline) enriched in connective tissue
Nitric oxide is a gaseous signaling molecule that regulates vascular tone, inflammation, and cell survival
Because both vitamins affect red cell size, a raised MCV can also be a clue when the B12 looks comfortable