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The increased RNS are highly reactive molecules which cause the nitrosative stress and react with various biomolecules of the cells and tissue of the airways and trigger a cascade of different mechanisms which causes cell damage, DNA damage, and mitochondrial and protein dysfunction to induce airway damage and airway hyperresponsiveness (Rahman et al

Wang WJ, et al

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Aging 12:1543615445 Xu X, Liu X, Tan L, Cui Z, Yang X, Zhu S, Li Z, Yuan X, Zheng Y, Yeung KWK, Chu PK, Wu S (2018) Controlled-temperature photothermal and oxidative bacteria killing and acceleration of wound healing by polydopamine-assisted Au-hydroxyapatite nano rods