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FDA approval requires a full review of safety, effectiveness, dosing, manufacturing, labeling, and risk information

Specific examples of what Peter is doing to prepare for his Centenarian Decathlon [39:30]

The disruption in BBB in the hippocampus is accelerated with MCI and ADRD progression compared to normal aging (Sweeney et al., 2018b)

Many of these placebo-controlled studies have demonstrated that folic acid supplementation improved symptoms in severely depressed patients, elderly depressed and demented patients, and those with major acute depression or schizophrenia, particularly in individuals with RBC folate levels below 453 nmol/L (46)

Early-life stress caused by maternal deprivation impacts dendritic morphology of adult male mouse neocortical interneurons

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