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2 The immunotherapeutic landscape of osteosarcoma: challenges and resistance mechanisms 2.1 The immunosuppressive TME The osteosarcoma TME is a complex ecosystem comprising malignant cells, stromal cells, immune infiltrates, and ECM components embedded within a mineralized bone scaffold (9, 22)

Mixed-meal tolerance test versus glucagon stimulation test for the assessment of -cell function in therapeutic trials in type 1 diabetes

Hylocereus undatus flower extract suppresses OVA-induced allergic asthma in BALb/c mice by reducing airway inflammation and modulating gut microbiota

Load Up on High-Fiber Foods at Every Meal Soluble fiber is the single strongest dietary trigger of GLP-1

These bioactive compounds exhibit dual functionalities, combining both antimicrobial and antioxidant properties

Epithelial HIF2 expression induces intestinal barrier dysfunction and exacerbation of arthritis