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doi: 10.1016/j.cmet.2016.01.006 229 ArnerPPetterssonAMitchellPJDunbarJDKharitonenkovARydnM

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Our results provide a possible mechanism in which upregulation of phosphorylated p53 and p16 maintain the cell cycle arrest of keloid fibroblasts, and FOXO4-DRI selectively induces apoptosis of keloid senescent fibroblasts by prompting p53-pS15 nuclear exclusion

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