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In its 2024 Challenges Report, the agency acknowledged it needs more funding to rebuild staff, shorten wait times, and improve the applicant experience

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How Ozempic Works: Semaglutide activates the GLP-1 receptor, enhancing insulin secretion when blood sugar is elevated, while simultaneously reducing glucagon release and slowing gastric emptying

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The combination of medical oversight, baseline pancreatic assessment, and periodic monitoring creates a safety framework that allows many at-risk patients to benefit from GLP-1 therapy responsibly