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doi: 10.3389/fendo.2025.1570603 Received 03 February 2025 Accepted 29 April 2025 Published 21 May 2025 Volume 16 - 2025 Edited by Jared Rutter, The University of Utah, United States Reviewed by Steven Patterson, Glasgow Caledonian University, United Kingdom Elena Jimenez Marti, University of Valencia, Spain Nigel Irwin, Ulster University, United Kingdom Updates Copyright 2025 Koefoed-Hansen, Helsted, Kizilkaya, Lund, Rosenkilde and Gasbjerg
Once metabolised, these compounds cannot cross the blood-brain barrier and contribute nothing to CNS effects
In specific clinical contexts (for example, certain patients on dialysis or with inherited deficiencies), carnitine may be compromised and the use of levocarnitine has a different rationale to general wellness use
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