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10.1186/s12866-020-01786-8 29 KoliadaA.SyzenkoG.MoseikoV.BudovskaL.PuchkovK.PerederiyV.et al (2017)

Fibroblasts can induce NP cells towards a fibrotic phenotype by activating TGF-/Smad signaling To examine the cellular effects of injected autologous DFbs on NP cells, we conducted in vitro cocultures of L929 fibroblastic cells and rat NP cells

Mixing peptides can cause degradation and loss of potency

In addition, nasal sprays provide specifically focused distribution into the nasal passages, where peptides can act systemically or locally

Cancer Lett 267(1):1825 Davies MA, Stemke-Hale K, Tellez C, Calderone TL, Deng W, Prieto VG, Lazar AJ, Gershenwald JE, Mills GB (2008) A novel AKT3 mutation in melanoma tumours and cell lines

Skin needs a lot of glutathione, so applying glutathione through your skin means the skin gets it first