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The researchers concluded that most of these hormonal changes (particularly TSH and free T3) appeared to be independent of weight loss, suggesting a possible direct effect of semaglutide on thyroid regulation that still needs to be clarified, while changes in free T4 were more closely related to weight change

Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-B pathway in ischemia/reperfusion injury after renal transplantation

Zhan, S

These medications are FDA-approved for the treatment of obesity, a chronic disease usually characterized by a BMI of 30 or higher

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doi:10.1001/jama.2021.3224 116