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MICHELLE: Stop it

Expansion of e-commerce channels for direct-to-consumer brands

The combination of phentermine, a psychostimulant, and topiramate, a carbonic anhydrase inhibitor, has been associated with increased heart rate (Alfaris 2015)

According to the PIONEER 3 trial, Rybelsus 3 mg reduced weight by an average of 0.6 kg at week 26

But if your concerns are more systemic (e.g., eczema, chronic wounds), an injectable may be better indicated

This raises questions about cost-effectiveness and access, but if priced reasonably or if generics eventually become available, we may see a broad shift where anti-obesity pharmacotherapy (especially GLP-1/GIP-based) is as commonplace as antihypertensive or lipid-lowering therapy