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The copper-binding tripeptide has been shown to stimulate collagen synthesis in fibroblast cell cultures, promote decorin and glycosaminoglycan production, and modulate expression of metalloproteinases (MMPs) involved in extracellular matrix remodeling in vitro

In psoriatic skin, NF-kB is constitutively activated, meaning it stays turned on even without an ongoing trigger

R., Sies, H

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The copper atom itself plays a role here, because copper-dependent enzymes such as superoxide dismutase (Cu/Zn-SOD) are central to endogenous antioxidant defense