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BPC-157 operates primarily at the local tissue level: it upregulates VEGF and EGF expression at the injury site, modulates the nitric oxide system to improve blood flow to damaged tissue, and directly promotes fibroblast migration and collagen organization through the FAK-paxillin pathway
In addition to stimulating GLP-1 receptors, it also targets GIP receptors
Va oral: biodisponibilidad considerablemente menor pero funcionalmente activa debido a actividad local en mucosa GI y posible absorcin peptdica intacta parcial va transportadores PepT1
Weight loss curves at the highest doses had not fully plateaued at the study endpoints, suggesting even greater losses with extended treatment
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