A big reason coverage can be so inconsistent is that insurance plans arent actually required by law to cover medications prescribed specifically for weight loss
Mazdutide, still in testing, shows promise with up to 15%
The preclinical literature has described effects across multiple pathways, and mechanistic claims are better framed as a family of related observations rather than a settled mechanism
Ong LT, Sia CH (2025) Interactions between antidiabetes medications and heart-brain axis
Instead, focus on eating glutathione precursors (like amino acids: cysteine, glycine, and glutamic acid), cofactors (like selenium and vitamin C), and other healthy, whole foods that give your body the energy and components it needs to synthesize glutathione may be more impactful (1)
International Diabetes Federation IDF Diabetes Atlas 10th edn (International Diabetes Federation, 2021)