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In the most recent clinical trials, less than 5% of people discontinued GLP-1 medications because of side effects
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(PubMed) Mariotti M, Ridge PG, Zhang Y, et al
Some initial cloudiness resolves as the peptide fully dissolves
The main differences are vial sizes (semaglutide commonly comes in 5 mg and 10 mg vials) and dosing ranges (semaglutide doses run 0.25 mg to 2.4 mg, lower than tirzepatide)
Augusta University Belsham DD et al (2009) Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
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