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EVOKE and EVOKE+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimers disease

doi: 10.2337/dbi21-0006 5 ZammouriJVatierCCapelEAuclairMStorey-LondonCBismuthEet al

On the other hand, the research of Fukuda and co-researchers showed that there was a significant negative correlation between blood ammonia and free carnitine concentrations in epileptic children ( P = 0.003) and this high serum level of ammonia was associated with increased severity of seizures in their series of patients 25