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Some GPs can prescribe Wegovy but this isnt yet a national standard
As an example illustrating the present invention, histidine has a predominant positive net charge below pH~6.5, thus for cation exchange the pH elution gradient with a solvent comprising an organic solvent or modifier could begin below pH 6.5 to remove a truncated form missing histidine and end the gradient above pH 6.5 thereby subsequently eluting the target GLP-1 moiety
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These organic acids include p-coumaric (4-hydroxycinnamic), caffeic (3,4-dihydroxycinnamic), ferulic (4-hydroxy-3-methoxycinnamic), and sinapic (3,5-dimethoxy-4-hydroxycinnamic) acids