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Notably, no redundant mitochondrial transporter compensates for CAC deficiency, making it indispensable for cellular life
The next blockbuster may not be a better diabetes drug
Their sustained presence may perpetuate a cycle of neurodegeneration, impaired redox homeostasis, and disrupted neurotransmitter turnover, all of which are altered in T21 21,30
Selected references are below: Recent Advances in Our Understanding of Mast Cell Activation - Or Should It Be Mast Cell Mediator Disorders
acknowledges the support of an Emmy Noether Award from the German Research Foundation (DFG, 467788900) and the Ministry of Culture and Science of the State of North Rhine-Westphalia (NRW-Nachwuchsgruppenprogramm)
doi: 10.1016/j.hemonc.2020.08.005 60
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