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Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Womens Heart and Health Study and Meta-Analysis
2023 Jul;39(7):699-709
Lowering GSH levels also triggers ferroptosis through deactivation of GPX4, leading to accumulation of lipid peroxides [87] In some cases, GSH depletion alone can induce therapeutic effects without relying on Fenton chemistry, which typically involves HO reacting with Fe 2 to form hydroxyl radicals (OH) that damage critical biomolecules such as DNA, proteins, and lipids
According to a case report by Otto ND and colleagues, intravenous glutathione therapy resulted in both subjective and objective symptom improvement for a patient with Parkinsons disease who was being conventionally treated
[PMID: 27581922] PubMed record related to this compound for laboratory literature review
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