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Research specifically examining menopausal status found no significant difference in weight loss between premenopausal, perimenopausal, and postmenopausal women using tirzepatide

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Anyone with a family or personal history or medullary thyroid cancer or other endocrine neoplasia should not take a GLP-1 medications

Obesity and obstructive sleep apnea are highly correlated a significant portion of patients seeking GLP-1 therapy for weight management also have documented sleep apnea

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doi: 10.7759/cureus.27335 46