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These glucagon-based chimeric peptides were generated by amino acid substitutions to the glucagon sequence aimed at increasing potency at the GLP-1R and conferring balanced co-agonism at both receptors

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Read more in relation to this - #ClinicalTrials #ObesityTreatment #GLP1 #PharmaInnovation #Biotech #DrugDevelopment To view or add a comment, sign in Structure Therapeutics announced Phase 2 topline data on aleniglipron - their once-daily oral small-molecule GLP-1 receptor agonist