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It may act like immunosuppressants also may interfere with tacrolimus and cyclosporine
Dev Med Child Neurol 47:403407
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Factors conferring relative protection to children from the toxic effect of paracetamol overdose include increases in paracetamol sulphation capacity [44,45,46,47,48], relative immaturity of the CYP450 oxidation system [15, 46, 49, 51] and the larger relative liver volume found in children [59] but these theoretical mechanisms have not been confirmed
Pang, Z
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