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PHARMACOKINETICS OF INTRAVENOUS LIPOIC ACID In published studies, intravenously administered alpha-lipoic acid (ALA) has been described as distributing rapidly into tissues and undergoing metabolic transformation predominantly through -oxidation and conjugation pathways in the liver

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doi: 10.1038/s41398-021-01583-5 130 ZhangSZhouNLiuRRaoWYangMCaoBet al

Some people also give themselves injections under the skin

Confusing topical and injectable doses