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Results: After 12 weeks of berberine supplementation (1,000 mg/day), she experienced a 10% reduction in body weight and improved insulin sensitivity

Maslowski KM, Mackay CR

Glutathione is the liver's major antioxidant, often depleted in fatty liver disease due to oxidative stress and inflammation

Studies are ongoing into the reasons for this, but many scientists believe there is a link between low glutathione levels and cell death

Importantly, insulin resistance worsens with age even in individuals without overt disease, reducing metabolic resilience and elevating lifetime risk