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8,9 Table 1 Risk Factors for Vitamin B12 Deficiency A multicenter randomized controlled trial of 390 patients with diabetes mellitus showed that those taking 850 mg of metformin three times per day had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years) vs

Supplements & Injections: Since the body cannot produce its own vitamin B12, it must be obtained through food, supplements, or injections

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GLP-1 Alternatives: Exploring Your Options When to Consider Alternatives You might explore GLP-1 alternatives if: Cost is a primary concern Insurance doesnt cover preferred brands Youve experienced side effects with one medication Availability issues with your current prescription Types of Alternatives Generic or biosimilar versions Compounded medications Different GLP-1 formulations Combination therapies Non-GLP-1 weight loss medications Starting Your GLP-1 Journey: A Beginners Guide Step 1: Medical Evaluation Before starting any GLP-1 medication, including MedVI, youll need: Comprehensive medical history review Current medication assessment BMI and weight loss goal evaluation Discussion of potential side effects Step 2: Insurance and Cost Planning Questions to ask your insurance provider: Which GLP-1 medications are covered

Animal studies show that mast cell stabilizing agents (cromolyn and ketotifen) can reduce both obesity and diabetes