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Preclinical studies of GLP-1 pathways have raised questions about inflammation, microglia, astrocytes, and neuroprotection
Romera I, Cebrin-Cuenca A, lvarez-Guisasola F, Gomez-Peralta F, Reviriego J
This natural stimulation helps maintain balanced growth hormone levels and reduces the risk of dependency or significant hormonal imbalances
However, the safest treatment depends on the patient, not the trend
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A change in diabetes drug prescribing led to clinical trials of intranasal insulin administration, followed by insulin sensitizers, including metformin and peroxisome proliferator-activated receptor agonists, followed by incretin mimetics targeting primarily GLP-1R (GLP-1RAs) [106]
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