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His fasting insulin level decreased from 25.6 to 14.9, representing improved insulin resistance (Fig

This paper highlights the importance of DNA damage as a contributory pathophysiological mechanism in ALS

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Dysregulation of this pathway can bias TRP metabolism toward neurotoxic and pro-inflammatory metabolites, thereby amplifying excitotoxicity, oxidative stress, and immune-driven disturbances in glutamatergic and monoaminergic neurotransmission

These naturally occurring compounds are designed to target specific physiological processes