Alterations in the normal function of excitatory amino acid carrier 1 affect cysteine transport and GSH synthesis impairing zinc homeostasis (the thiol group of GSH can function as a principal Zn 2+ chelator for the maintenance of Zn 2+ homeostasis in neurons) and oxidative stress, enhancing susceptibility to ischemia-induced neuronal cell death in the hippocampus (162164)
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Corsi, C., Pollastri, M., Marrapodi, E., Leanza, D., Giordano, S., and D'Iddio, S
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PubMed Copper supports regulatory T cell energetic state to sustain peripheral