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Nicotinamide (NAM), a known inhibitor of SIRT1, and SR-18292, a selective inhibitor of PGC-1 activity
Enhanced local blood supply supports the metabolic demands of repair
Nonetheless, researchers are advised to avoid excessive use and contaminants
Although the treated mice did not develop more skin tumors than similar mice that had not been fed the antioxidants, they developed twice as many tumors in their lymph nodes, a hallmark of the spread of cancera process called metastasis
The incidence of severe oral mucositis was significantly lower, and the duration shorter, in the NAC-treated group (Moslehi 2014)
