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Patient selection for clinical trials should reflect the pathophysiologic subtype of hyperuricemia, existing comorbidities, and concurrent use of urine alkalization agents such as potassium citrate

For example, scientists at Arizona State University found that the interior of a car can reach more than 100F within an hour on a summer day, even when parked in the shade

How It Works (Step-by-Step) Fill out a short online medical form (about 5 minutes) Meet with a licensed provider via telehealth (usually within 24 hours) If approved, your prescription is processed and shipped (810 business days) Start treatment and check in with your provider as needed Geographic Availability Not available in AL, AK, AR, HI, LA, MS, MO, SC, WV Clinical Oversight and Safety Qualified and licensed nurse practitioners or physician assistants Follow-up labs only at the provider's discretion Patient portal for reporting side effects and adjusting treatment plan Clinician messaging during regular business hours Treatments Offered Weekly or biweekly GLP-1 injections: compounded semaglutide Daily GLP-1 injections: compounded liraglutide Daily oral GLP-1 options: compounded semaglutide pills or drops

Wightman EL, Jackson PA, Spittlehouse B, Heffernan T, Guillemet D, Kennedy DO

10.1371/journal.pone.0143660 18 FrugierT.TaylorJ

doi: 10.1186/s12974-020-02057-z 66 ChuHXKimHALeeSMooreJPChanCTVinhAet al