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[1] [2] Clinical trials demonstrated substantial weight loss, with participants in the SURMOUNT-1 trial (primarily non-diabetic adults) losing an average of 15-21% of body weight over 72 weeks, with somewhat smaller reductions observed in people with type 2 diabetes

The activity level of parthanatos was decreased, while the activity level of LDCD was increased in DKD compared with control, as shown by a bioinformatic study (135)

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